Plasma sufentanil concentration after intranasal administration to paediatric outpatients
نویسندگان
چکیده
منابع مشابه
Intranasal sufentanil/ketamine analgesia in children.
BACKGROUND The management of procedural pain in children ranges from physical restraint to pharmacological interventions. Pediatric formulations that permit accurate dosing, are accepted by children and a have a rapid onset of analgesia are lacking. OBJECTIVES To investigate a pediatric formulation of intranasal sufentanil 0.5 mcg·kg(-1) and ketamine 0.5 mg·kg(-1) for procedural pain and to c...
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The aim of this study is to determine whether baicalin can be transferred along the olfactory pathway to the brain after nasal administration of baicalin phospholipid (BP) complex to rats, thereby circumventing the blood brain barrier. The concentration of baicalin in plasma and different brain tissues (olfactory bulb, cerebral cortex, striatum and cerebellum) were measured by high-performance ...
متن کاملMedication errors in paediatric outpatients.
BACKGROUND Medication errors are common in many settings and have important ramifications. Although there is growing research on rates and characteristics of medication errors in adult ambulatory settings, less is known about the paediatric ambulatory setting. OBJECTIVE To assess medication error rates in paediatric patients in ambulatory settings. METHODS The authors conducted a prospectiv...
متن کاملIntranasal administration of drugs.
OBJECTIVE To investigate how nasally applied substances distribute in the nose depending on the form of application. DESIGN Observer-blinded study. SETTING University hospital research unit. PARTICIPANTS Fifteen healthy volunteers aged 22 to 32 years. INTERVENTIONS Forms of application included (1) nasal drops applied with a pipette, (2) nasal spray, and (3) a system producing squirts. ...
متن کاملIntranasal sufentanil is effective for postoperative analgesia in adults.
PURPOSES The aim of this prospective, randomized, double-blind study was to compare two doses of intranasal sufentanil for postoperative analgesia, titrated according to individual requirements based upon a numeric rating scale (NRS) from 0 to 10 for pain. METHODS Forty patients, American Society of Anesthesiologists physical status I-II, scheduled for herniorrhaphy or hemorrhoidectomy under ...
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ژورنال
عنوان ژورنال: Canadian Journal of Anaesthesia
سال: 1993
ISSN: 0832-610X,1496-8975
DOI: 10.1007/bf03037044